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BioProcess International Special Report: Delivering on the Promise of Bispecifics

Posted by Selexis admin on Jun 22, 2022 11:08:51 AM
June 22, 2022

An off-the-shelf therapy that can be used immediately, rather than one that must be manufactured individually for each patient (such as chimeric antigen receptor T-cell therapies, or CAR-Ts), can be a life-saving treatment for patients who encounter difficult-to-treat or rapidly progressing diseases, including many cancers. The promise of bispecific antibodies (bsAbs) stems from their off-the-shelf nature and ability to bind to two or more different targets or epitopes, thereby performing multiple functions.

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Keywords: clonal cell lines, chinese hamster ovary cells, transient transfection, expression pools, SUREtechnology Platform, CHO cells