Selexis and KBI Biopharma Enter into Agreements with Immatics for Integrated Approach to Advance Immatics TCR Bispecific Program Towards INDRead More
Selexis Genetic Elements are proprietary epigenetic DNA-based elements that boost protein expression by controlling the dynamic organization of chromatin around the recombinant gene integration sites. The SGEs facilitate opening of the chromatin and stabilization of the transgene integration, which in turn allows for higher and sustained expression of recombinant proteins, even with multi-gene integrations.
- Facilitated opening of chromatin
- Enhanced transcription
- Stabilization of transgene integration
- Sustained multigene expression